Rafael Dariolli

Short Bio

Postdoctoral fellow researcher working in Lab. Genetics and Molecular Cardiology, Heart Institute InCor (current bond), under the supervision of Dr. Jose Eduardo Krieger. Developing studies in Cardiac Regeneration based in cell therapy, induced pluripotent stem cells among other approaches. Postdoctoral fellow researcher in Icahn School of Medicine at Mount Sinai, New York, USA (2016-2017), developing studies in bioinformatics and mathematical modeling of prediction to with emphasis in drug-tests, ion channels, etc, based on electrophysiology of cardiac cells. Experience in General Biology, with emphasis in molecular and cellular biology, DNA manipulation (Adenovirus, Lentivirus, TALEN, CRISPR), experimental medicine, developing small and large animal modeling and experimental echocardiography/ultrasound. Doctor in Science ? Cellular and Molecular biology at University of Sao Paulo/Medical School. Master in Science at University of Sao Paulo/Medical School. Bachelor degree in biology at Universidade Estadual Paulista ?Júlio de Mesquita Filho?.

Line of Investigation

  • Cardiac Regeneration: Use of alternative therapies aiming heart regeneration after myocardial injury
  • Transthoracic echocardiography: Basic and applied research
  • DNA manipulation - development of cellular and animal transgenic models

Publications

  1. MALAGRINO, P. A.;VENTURINI, G.;YOGI, P. S.;DARIOLLI, R.;PADILHA, K.;KIERS, B.;GOIS, T. C.;MOTTA-LEAL-FILHO, J. M.;TAKIMURA, C.;GIRARDI, A. C. C.;CARNEVALE, F. C.;ZERI, A. C. M.;MALHEIROS, D. M. A. C.;KRIEGER, J. E.;PEREIRA, A. C.;.Catheter-based induction of renal ischemia/reperfusion in swine: description of an experimental model. Physiological Reports,v.2,e12150 - e12150,2014;
  2. JENSEN, LEONARDO;NERI, ELIDA;BASSANEZE, VINICIUS;ALMEIDA OLIVEIRA, NATHALIA CORRÊA DE;Dariolli, Rafael;TURAÇA, THIAGO LAURO;LEVY, DÉBORA;VERONEZ, DOUGLAS;AYRES FERRAZ, MARIANA SACRINI;ALENCAR, ADRIANO MESQUITA;BYDLOWSKI, SÉRGIO PAULO;CESTARI, IDÁGENE APARECIDA;KRIEGER, JOSÉ EDUARDO;.Integrated molecular, biochemical, and physiological assessment unravels key extraction method mediated influences on rat neonatal cardiomyocytes. JOURNAL OF CELLULAR PHYSIOLOGY,v.1,1 - 31,2018;
  3. Dariolli, Rafael;NAGHETINI, MARCUS V.;MARQUES, EUCLYDES F.;TAKIMURA, CELSO K.;JENSEN, LEONARDO S.;KIERS, BIANCA;TSUTSUI, JEANE M.;MATHIAS, WILSON;LEMOS NETO, PEDRO A.;KRIEGER, JOSE E.;.Allogeneic pASC transplantation in humanized pigs attenuates cardiac remodeling post-myocardial infarction. PLoS One,v.12,e0176412,2017;
  4. STEICHEN, C.;SI-TAYEB, K.;WULKAN, F.;CRESTANI, T.;ROSAS, G.;DARIOLLI, R.;PEREIRA, A. C.;KRIEGER, J. E.;.Human Induced Pluripotent Stem (hiPS) Cells from Urine Samples: A Non-Integrative and Feeder-Free Reprogramming Strategy. Current Protocols in Human Genetics,v.21,1 - 22,2017;
  5. MALAGRINO, PAMELLA ARAUJO;VENTURINI, GABRIELA;YOGI, PATRÍCIA SCHNEIDER;Dariolli, Rafael;PADILHA, KALLYANDRA;KIERS, BIANCA;GOIS, TAMIRIS CARNEIRO;CARDOZO, KARINA HELENA MORAIS;CARVALHO, VALDEMIR MALECHO;SALGUEIRO, JÉSSICA SILVA;GIRARDI, ADRIANA CASTELLO COSTA;TITAN, SILVIA M.O.;KRIEGER, JOSÉ EDUARDO;PEREIRA, ALEXANDRE COSTA;.Proteome analysis of acute kidney injury - Discovery of new predominantly renal candidates for biomarker of kidney disease. Journal of Proteomics (Print),v.,1/8 - 8,2016;
  6. ARRUDA-JUNIOR, DANIEL F.;MARTINS, FLAVIA L.;Dariolli, Rafael;JENSEN, LEONARDO;ANTONIO, EDNEI L.;DOS SANTOS, LEONARDO;TUCCI, PAULO J. F.;GIRARDI, ADRIANA C. C.;.Dipeptidyl Peptidase IV Inhibition Exerts Renoprotective Effects in Rats with Established Heart Failure. Frontiers in Physiology,v.7,1/293 - 16,2016;
  7. MALAGRINO, PAMELLA ARAUJO;VENTURINI, GABRIELA;YOGI, PATRÍCIA SCHNEIDER;Dariolli, Rafael;PADILHA, KALLYANDRA;KIERS, BIANCA;GOIS, TAMIRIS CARNEIRO;MOTTA-LEAL-FILHO, JOAQUIM MAURÍCIO;TAKIMURA, CELSO KIYOCHI;GIRARDI, ADRIANA CASTELLO COSTA;CARNEVALE, FRANCISCO CÉSAR;CANEVAROLO, RAFAEL;MALHEIROS, DENISE MARIA AVANCINI COSTA;DE MATTOS ZERI, ANA CAROLINA;KRIEGER, JOSÉ EDUARDO;PEREIRA, ALEXANDRE COSTA;.Metabolomic characterization of renal ischemia and reperfusion in a swine model. Life Sciences (1973),v.156,57/67,2016;
  8. ALVES, C. J.;DARIOLLI, R.;JORGE, F. M.;MONTEIRO, M. R.;MAXIMINO, J. R.;MARTINS, R. S.;STRAUSS, B. E.;KRIEGER, J. E.;CALLEGARO, D.;CHADI, G.;.Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration. Frontiers in Cellular Neuroscience,v.9,1/289,2015;
  9. DARIOLLI, R.;TAKIMURA, C.;CAMPOS, C. A.;LEMOS NETO, P. A.;KRIEGER, J. E.;.Development of a closed-artery catheter-based myocardial infarction in pigs using sponge and lidocaine hydrochloride infusion to prevent irreversible ventricular fibrillation. Physiological Reports,v.2,e12121 - e12121,2014;
  10. LIMA, V. D. S.;Crajoinas, R. O.;Carraro-Lacroix, L. R.;GODINHO, A. N.;DIAS, J. L. G.;DARIOLLI, R.;Girardi, A. C. C.;Fonteles, M. C.;Malnic, G.;Lessa, L. M. A.;.Uroguanylin inhibits H-ATPase activity and surface expression in renal distal tubules by a PKG dependent pathway. AJP: Cell Physiology,v.307,C-00392-2013,2014;
  11. DINARDO, C. L.;VENTURINI, G.;ZHOU, E. H.;WATANABE, I.;CAMPOS, L. C.;DARIOLLI, R.;MOTTA-LEAL-FILHO, J. M.;CARVALHO, V. M.;MORAIS CARDOZO, K. H.;KRIEGER, J. E.;ALENCAR, A. M.;PEREIRA, A. C.;.Variation of mechanical properties and quantitative proteomics of VSMC along the arterial tree. American Journal of Physiology. Heart and Circulatory Physiology,v.306,H505 - H516,2013;
  12. DARIOLLI, R.;BASSANEZE, V.;NAKAMUTA, J. S.;OMAE, S. V.;CAMPOS, L. C.;KRIEGER, J. E.;.Porcine Adipose Tissue-Derived Mesenchymal Stem Cells Retain Their Proliferative Characteristics, Senescence, Karyotype and Plasticity after Long-Term Cryopreservation. Plos One,v.8,e67939,2013;
  13. DINARDO, C. L.;VENTURINI, G.;OMAE, S. V.;ZHOU, E. H.;MOTTA-LEAL-FILHO, J. M.;DARIOLLI, R.;KRIEGER, J. E.;ALENCAR, A. M.;PEREIRA, A. C.;.Vascular smooth muscle cells exhibit a progressive loss of rigidity with serial culture passaging. Biorheology (Oxford),v.49,365 - 373,2012;
  14. CARVALHO, R. F.;DARIOLLI, R.;JUSTULIN JUNIOR, L. A.;SUGIZAKI, M. M.;OKOSHI, M. P.;CICOGNA, A. C.;FELISBINO, S. L.;PAI-SILVA, M. D.;.Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle. International Journal of Experimental Pathology (Print),v.87,437 - 443,2006;
  15. Lessa, L. M. A.;Carraro-Lacroix, L. R.;Crajoinas, R. O.;BEZERRA, C. N.;DARIOLLI, R.;Girardi, A. C. C.;Fonteles, M. C.;Malnic, G.;.Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule. American Journal of Physiology. Renal Physiology,v.303,F1399 - F1408,2012;