Received the M.D. degree from the Univ São Paulo Med Sch (1984), Campus Ribeirao Preto., the Ph.D. degree in Physiology from the Medical College Of Wisconsin (1988), and Post-doctoral training in molecular biology at Harvard Medical School and Stanford University School of Medicine. He is Full Professor of Medicine at the University of Sao Paulo Medical School and Director of the Laboratory of Genetics and Molecular Cardiology at the Heart Institute (InCor). He is a regular member of the Brazilian and State of São Paulo Academies of Science and Peovost of Research at tge University of Sao Paulo. The main research areas focus on the identification of molecular markers associated with the genesis of cardiovascular diseases and the development of new therapeutic interventions based on gene/cell approaches.